Core Science

miRNA-Driven Cellular Reprogramming

Through deep functional analysis of microRNAs (miRNAs), LIVIUS has established a proprietary approach to cellular reprogramming that operates through endogenous regulatory networks. By precisely modulating miRNA activity, we are able to induce controlled changes in cellular state without relying on transcription factor–based methods. This core scientific foundation enables stable and reproducible reprogramming while preserving cellular integrity.

Epigenetic Gene Expression

Small-Molecule Control of Cellular State

Building on our miRNA science, LIVIUS has developed a strategy to induce similar cellular reprogramming using small-molecule compounds. By epigenetically regulating target gene expression, these compounds activate the same biological pathways identified in our miRNA research. This chemically controlled approach offers high reproducibility, scalability, and a clear path toward real-world application, accelerating the transition from discovery to commercialization.

This advanced technological framework positions LIVIUS at the forefront of biotechnology, pioneering solutions that have the potential to transform the treatment landscape for many previously intractable diseases.

Gene Mutation Repair

Evidence-Based DNA Damage Restoration

In parallel with cellular reprogramming, LIVIUS has confirmed—through experimental evidence—that DNA damage and gene mutations can be repaired during the reprogramming process. This simultaneous restoration of genomic integrity represents a critical step toward addressing diseases driven by genetic alterations. Establishing this capability as a therapeutic modality could open new possibilities for treating conditions rooted in accumulated DNA damage and mutation.